CARD11 Antikörper (AA 301-400)
Kurzübersicht für CARD11 Antikörper (AA 301-400) (ABIN715691)
Target
Alle CARD11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 301-400
- 
                                            Homologie
- Human,Mouse,Rat,Dog,Cow,Chicken
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human CARD11
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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                                            Andere Bezeichnung
- Card11
- 
                                            Hintergrund
- 
                        Synonyms: Bcl10 interacting maguk protein 3, BIMP 3, BIMP3, CAR11_HUMAN, CARD 11, CARD containing MAGUK protein 3, Card maguk protein 1, CARD-containing MAGUK protein 1, CARD11, CARD11 protein, Carma 1, CARMA1, Caspase recruitment domain containing protein 11, Caspase recruitment domain family member 11, Caspase recruitment domain-containing protein 11, MGC133069. Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. 
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                                            Gen-ID
- 84433
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                                            Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling
 Target
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