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CARD11 Antikörper (AA 301-400)

This anti-CARD11 antibody (ABIN715691) is a Rabbit Polyclonal antibody detecting CARD11 in WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro). Suitable for Human.
Produktnummer ABIN715691

Kurzübersicht für CARD11 Antikörper (AA 301-400) (ABIN715691)

Target

Alle CARD11 Antikörper anzeigen
CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Reaktivität

  • 33
  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 31
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 32
  • 2
Polyklonal

Konjugat

  • 27
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CARD11 Antikörper ist unkonjugiert

Applikation

  • 27
  • 10
  • 9
  • 9
  • 6
  • 4
  • 4
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 301-400

    Homologie

    Human,Mouse,Rat,Dog,Cow,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CARD11

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

    Andere Bezeichnung

    Card11

    Hintergrund

    Synonyms: Bcl10 interacting maguk protein 3, BIMP 3, BIMP3, CAR11_HUMAN, CARD 11, CARD containing MAGUK protein 3, Card maguk protein 1, CARD-containing MAGUK protein 1, CARD11, CARD11 protein, Carma 1, CARMA1, Caspase recruitment domain containing protein 11, Caspase recruitment domain family member 11, Caspase recruitment domain-containing protein 11, MGC133069.

    Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

    Gen-ID

    84433

    Pathways

    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling
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