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CARD11 Antikörper (AA 301-400)

Der Kaninchen Polyklonal Anti-CARD11-Antikörper wurde für WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet, CARD11 in Proben von Human zu detektieren.
Produktnummer ABIN715691

Kurzübersicht für CARD11 Antikörper (AA 301-400) (ABIN715691)

Target

Alle CARD11 Antikörper anzeigen
CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Reaktivität

  • 33
  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 31
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 32
  • 2
Polyklonal

Konjugat

  • 27
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CARD11 Antikörper ist unkonjugiert

Applikation

  • 27
  • 10
  • 9
  • 9
  • 6
  • 4
  • 4
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 301-400

    Homologie

    Human,Mouse,Rat,Dog,Cow,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CARD11

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

    Andere Bezeichnung

    Card11

    Hintergrund

    Synonyms: Bcl10 interacting maguk protein 3, BIMP 3, BIMP3, CAR11_HUMAN, CARD 11, CARD containing MAGUK protein 3, Card maguk protein 1, CARD-containing MAGUK protein 1, CARD11, CARD11 protein, Carma 1, CARMA1, Caspase recruitment domain containing protein 11, Caspase recruitment domain family member 11, Caspase recruitment domain-containing protein 11, MGC133069.

    Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

    Gen-ID

    84433

    Pathways

    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling
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