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TLR7 Antikörper (AA 420-644)

Dieses Anti-TLR7-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TLR7 in ELISA, FACS und ICC. Geeignet für Human.
Produktnummer ABIN7193967

Kurzübersicht für TLR7 Antikörper (AA 420-644) (ABIN7193967)

Target

Alle TLR7 Antikörper anzeigen
TLR7 (Toll-Like Receptor 7 (TLR7))

Reaktivität

  • 95
  • 45
  • 9
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 93
  • 19
Maus

Klonalität

  • 81
  • 30
  • 1
Monoklonal

Konjugat

  • 67
  • 8
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
Dieser TLR7 Antikörper ist unkonjugiert

Applikation

  • 65
  • 48
  • 33
  • 17
  • 14
  • 10
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon

4G1D4
  • Bindungsspezifität

    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-644

    Verwendungszweck

    TLR7 Antibody

    Aufreinigung

    Purified antibody

    Immunogen

    Purified recombinant fragment of human TLR7 (AA: 420-644) expressed in E. Coli.

    Isotyp

    IgG2b
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50 - 1/200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target

    TLR7 (Toll-Like Receptor 7 (TLR7))

    Andere Bezeichnung

    TLR7

    Hintergrund

    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. The human TLR family comprises 11 members. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. For the recognition of structural components in foreign microorganisms, the various TLRs exhibit different patterns of expression as well, in this way for example, TLR-3, -7, and -8 are essential in the recognition of single-stranded RNA viruses. TLR7 senses single-stranded RNA oligonucleotides containing guanosine- and uridine-rich sequences from RNA viruses, a recognition occuring in the endosomes of plasmacytoid dendritic cells and B cells. This gene is predominantly expressed in lung, placenta, and spleen, and is phylogenetically related and lies in close proximity to another family member, TLR8, on chromosome X.

    Molekulargewicht

    120 kDa

    Gen-ID

    51284

    UniProt

    Q9NYK1

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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