FASL Antikörper (AA 103-281)

Produktnummer ABIN7193839

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FASL in FACS, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FASL Antikörper (AA 103-281) (ABIN7193839)

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FASL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Klon: 2A6E12

Produktdetails anti-FASL Antikörper

Bindungsspezifität: AA 103-281

Verwendungszweck: CD178 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD178 (AA: 103-281) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu FASL

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Andere Bezeichnung: CD178

Hintergrund:

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Molekulargewicht: 31.5 kDa

Gen-ID: 356

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity