IGF1R Antikörper
Kurzübersicht für IGF1R Antikörper (ABIN7193763)
Target
Alle IGF1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- IGF1R Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.
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Isotyp
- IgG2a
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anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R Reaktivität: Human FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibodyIGF1R Reaktivität: Human WB, IHC, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1335-1366), (C-Term) antibodyIGF1R Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB01458 unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77), (N-Term) antibodyIGF1R Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB15292 unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibodyIGF1R Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibodyIGF1R Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 763-955) antibodyIGF1R Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1-1367) antibodyIGF1R Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 19-51), (N-Term) antibodyIGF1R Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1455-1456 unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibodyIGF1R Reaktivität: Human, Maus, Ratte, Affe WB, IHC, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Andere Bezeichnung
- IGF1R
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Hintergrund
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This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Molekulargewicht
- 154.8 kDa
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UniProt
- P08069
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Pathways
- RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie
Target
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