MR1 Antikörper

Produktnummer ABIN7193762

Der Maus Monoklonal Anti-MR1-Antikörper wurde für ELISA, IHC, FACS und ICC validiert. Er ist geeignet, MR1 in Proben von Human zu detektieren.

Kurzübersicht für MR1 Antikörper (ABIN7193762)

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 6A5B2

Produktdetails anti-MR1 Antikörper

Verwendungszweck: MR1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MR1 (AA: extra(23-302)) expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu MR1

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Andere Bezeichnung: MR1

Hintergrund:

MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

Molekulargewicht: 39.4 kDa

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints