GZMB Antikörper (AA 21-247)
Kurzübersicht für GZMB Antikörper (AA 21-247) (ABIN7193680)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 21-247
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Verwendungszweck
- GZMB Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli.
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Isotyp
- IgG2a
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- GZMB (Granzyme B (GZMB))
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Andere Bezeichnung
- GZMB
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Hintergrund
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This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
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Molekulargewicht
- 28 kDa
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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