COL1A2 Antikörper (AA 23-79)
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- Target Alle COL1A2 Antikörper anzeigen
- COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
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Bindungsspezifität
- AA 23-79
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser COL1A2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- COL1A2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human COL1A2 (AA: 23-79) expressed in E. Coli.
- Klon
- 4D1A7
- Isotyp
- IgG1
- Top Product
- Discover our top product COL1A2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
- Andere Bezeichnung
- COL1A2 (COL1A2 Produkte)
- Hintergrund
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Description:
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Aliases: OI4, EDSCV, EDSARTH2
- Molekulargewicht
- 129kDa
- Gen-ID
- 1278
- UniProt
- P08123
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