MSH2 Antikörper (AA 442-586)
Kurzübersicht für MSH2 Antikörper (AA 442-586) (ABIN7193496)
Target
Alle MSH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 442-586
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Verwendungszweck
- MSH2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Andere Bezeichnung
- MSH2
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Hintergrund
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This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 104.7 kDa
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Gen-ID
- 4436
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UniProt
- P43246
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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