IL15RA Antikörper (AA 31-205)

Produktnummer ABIN7193409

Dieses Anti-IL15RA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL15RA in WB und ELISA. Geeignet für Human.

Kurzübersicht für IL15RA Antikörper (AA 31-205) (ABIN7193409)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL15RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 5F10D9

Produktdetails anti-IL15RA Antikörper

Bindungsspezifität: AA 31-205

Verwendungszweck: CD215 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD215 (AA: 31-205) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Andere Bezeichnung: CD215

Hintergrund:

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]

Molekulargewicht: 28.2 kDa

Pathways: JAK-STAT Signalweg