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IDH2 Antikörper (AA 1-143)

Dieses Anti-IDH2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IDH2 in IHC, ELISA und FACS. Geeignet für Human.
Produktnummer ABIN7193379

Kurzübersicht für IDH2 Antikörper (AA 1-143) (ABIN7193379)

Target

Alle IDH2 Antikörper anzeigen
IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reaktivität

  • 72
  • 55
  • 45
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 61
  • 10
  • 1
Maus

Klonalität

  • 54
  • 18
Monoklonal

Konjugat

  • 38
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IDH2 Antikörper ist unkonjugiert

Applikation

  • 52
  • 18
  • 17
  • 17
  • 13
  • 13
  • 9
  • 9
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon

3E8E9
  • Bindungsspezifität

    • 16
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-143

    Verwendungszweck

    IDH2 Antibody

    Aufreinigung

    Purified antibody

    Immunogen

    Purified recombinant fragment of human IDH2 (AA: 1-143) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target

    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

    Andere Bezeichnung

    IDH2

    Hintergrund

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

    Molekulargewicht

    50.9 kDa

    Gen-ID

    3418

    UniProt

    P48735

    Pathways

    Warburg Effekt
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