TLR3 Antikörper (AA 24-217)

Produktnummer ABIN7193368

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TLR3 in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TLR3 Antikörper (AA 24-217) (ABIN7193368)

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TLR3 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 6F3G4

Produktdetails anti-TLR3 Antikörper

Bindungsspezifität: AA 24-217

Verwendungszweck: CD283 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD283 (AA: 24-217) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu TLR3

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Andere Bezeichnung: CD283

Hintergrund:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]

Molekulargewicht: 103.8 kDa

UniProt: O15455

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades