IL5RA Antikörper (AA 21-196)
Kurzübersicht für IL5RA Antikörper (AA 21-196) (ABIN7193317)
Target
Alle IL5RA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 21-196
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Verwendungszweck
- CD125 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD125 (AA: 21-196) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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Andere Bezeichnung
- CD125
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Hintergrund
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The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
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Molekulargewicht
- 47.7 kDa
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Gen-ID
- 3568
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Pathways
- JAK-STAT Signalweg
Target
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