IL13 Receptor alpha 1 Antikörper (AA 22-343)

Produktnummer ABIN7193280

Dieses Anti-IL13 Receptor alpha 1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL13 Receptor alpha 1 in WB, ELISA und FACS. Geeignet für Human.

Kurzübersicht für IL13 Receptor alpha 1 Antikörper (AA 22-343) (ABIN7193280)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL13 Receptor alpha 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 8A3E3

Produktdetails anti-IL13 Receptor alpha 1 Antikörper

Bindungsspezifität: AA 22-343

Verwendungszweck: CD213A1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD213A1 (AA: 22-343) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Andere Bezeichnung: CD213A1

Hintergrund:

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Molekulargewicht: 48.8 kDa

Gen-ID: 3597

UniProt: P78552

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response