CD46 Antikörper (AA 35-179)

Produktnummer ABIN7193209

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD46 in WB, FACS, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD46 Antikörper (AA 35-179) (ABIN7193209)

Target: CD46

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Klon: 5A8C11

Produktdetails anti-CD46 Antikörper

Bindungsspezifität: AA 35-179

Verwendungszweck: CD46 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46

Hintergrund:

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht: 43.7 kDa

Gen-ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization