CD46 Antikörper (AA 35-179)
Kurzübersicht für CD46 Antikörper (AA 35-179) (ABIN7193208)
Target
Alle CD46 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 35-179
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Verwendungszweck
- CD46 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.
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Isotyp
- IgG1
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anti-CD46 (CD46) (AA 40-320) antibody
CD46 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 Reaktivität: Human WB, FACS, ELISA, ICC Wirt: Maus Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reaktivität: Human WB, FACS, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 Reaktivität: Human, Maus WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibody (Biotin)CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (FITC)CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 FITC
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Monoclonal 7D12 unconjugated Recombinant Antibody
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD46
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Andere Bezeichnung
- CD46
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Hintergrund
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The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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Molekulargewicht
- 43.7 kDa
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Gen-ID
- 4179
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UniProt
- P15529
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Pathways
- Regulation of Actin Filament Polymerization
Target
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