APOB Antikörper

Produktnummer ABIN7189848

Dieses Anti-APOB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von APOB in IHC und ELISA. Geeignet für Human.

Kurzübersicht für APOB Antikörper (ABIN7189848)

Target: APOB (Apolipoprotein B (APOB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-APOB Antikörper

Verwendungszweck: APOB Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human APOB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu APOB

Target: APOB (Apolipoprotein B (APOB))

Andere Bezeichnung: APOB

Hintergrund:

Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Aliases: Apo B 100 antibody, Apo B antibody, Apo B-100 antibody, Apo B-48 antibody, Apo B100 antibody, Apo B48 antibody, ApoB 100 antibody, ApoB 48 antibody, APOB antibody, APOB_HUMAN antibody, Apolipoprotein B (including Ag(x) antigen) antibody, Apolipoprotein B 100 antibody, Apolipoprotein B 48 antibody, Apolipoprotein B antibody, Apolipoprotein B-48 antibody, Apolipoprotein B100 antibody, Apolipoprotein B48 antibody, FLDB antibody, LDLCQ4 antibody

UniProt: P04114

Pathways: Lipid Metabolism