CTLA4 Antikörper (C-Term)

Produktnummer ABIN7189383

Dieses Anti-CTLA4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CTLA4 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für CTLA4 Antikörper (C-Term) (ABIN7189383)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CTLA4 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen Affinity Purified

Immunogen: Synthetic peptide corresponding to residues near the C terminal of Human Cytotoxic T-lymphocyte protein 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CTLA4

Hintergrund:

Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Aliases: ALPS5 antibody, CD 152 antibody, CD antibody, CD152 antibody, CD152 antigen antibody, CD152 isoform antibody, Celiac disease 3 antibody, CELIAC3 antibody, CTLA 4 antibody, CTLA-4 antibody, CTLA4 antibody, CTLA4_HUMAN antibody, Cytotoxic T cell associated 4 antibody, Cytotoxic T lymphocyte antigen 4 antibody, Cytotoxic T lymphocyte associated 4 antibody, Cytotoxic T lymphocyte associated 4, soluble isoform, included antibody, Cytotoxic T lymphocyte associated antigen 4 antibody, Cytotoxic T lymphocyte associated antigen 4 short spliced form antibody, Cytotoxic T lymphocyte associated protein 4 antibody, Cytotoxic T lymphocyte associated serine esterase 4 antibody, Cytotoxic T lymphocyte protein 4 antibody, Cytotoxic T-lymphocyte protein 4 antibody, Cytotoxic T-lymphocyte-associated antigen 4 antibody, GRD4 antibody, GSE antibody, ICOS antibody, IDDM12 antibody, insulin-dependent diabetes mellitus 12 antibody, Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody, OTTHUMP00000216623 antibody

UniProt: P16410

Pathways: Cancer Immune Checkpoints