CK1 epsilon Antikörper

Produktnummer ABIN7183325

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CK1 epsilon in WB, ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CK1 epsilon Antikörper (ABIN7183325)

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CK1 epsilon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CK1 epsilon Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human CKI-ε,.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CK1 epsilon

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Andere Bezeichnung: CSNK1E

Hintergrund:

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.

Fish K.J., J. Biol. Chem. 270:14875-14883(1995).
Okamura A., Blood 103:2997-3004(2004).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Aliases: Casein kinase 1 epsilon antibody, Casein kinase I antibody, Casein kinase I epsilon antibody, Casein kinase I isoform epsilon antibody, CKI epsilon antibody, CKI-epsilon antibody, CKIe antibody, CKIepsilon antibody, CSNK 1E antibody, CSNK1E antibody, DBT antibody, Doubletime, Drosophila, homolog of antibody, EC 2.7.11.1 antibody, epsilon isoform antibody, HCK IE antibody, KC1E antibody, KC1E_HUMAN antibody, kinase CK1 epsilon antibody, MGC 10398 antibody

UniProt: P49674

Pathways: Hedgehog Signalweg, M Phase