ITGAL Antikörper (PE)

Produktnummer ABIN7178494

Dieses Anti-ITGAL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGAL in FACS, IF und ELISA. Geeignet für Human.

Kurzübersicht für ITGAL Antikörper (PE) (ABIN7178494)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Produktdetails anti-ITGAL Antikörper (PE)

Kreuzreaktivität: Human

Aufreinigung: Affinity purified

Immunogen: Recombinant Protein

Isotyp: IgG1, IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution:IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: ITGAL

Hintergrund:

Background: 4A122 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate.1. Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16:479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99.

Aliases: N/A

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex