Calreticulin Antikörper (AA 18-417) (HRP)
Kurzübersicht für Calreticulin Antikörper (AA 18-417) (HRP) (ABIN7178244)
Target
Alle Calreticulin (CALR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 18-417
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Kreuzreaktivität
- Schwein
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Pig Calreticulin protein (18-417AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Calreticulin (CALR)
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Andere Bezeichnung
- CALR
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Hintergrund
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Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.
Aliases: CALRCalreticulin antibody, CRP55 antibody, Calregulin antibody, Endoplasmic reticulum resident protein 60 antibody, ERp60 antibody, HACBP antibody
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UniProt
- P28491
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
Target
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