Calreticulin Antikörper (AA 18-417)

Produktnummer ABIN7178241

Der Kaninchen Polyklonal Anti-Calreticulin-Antikörper wurde für ELISA validiert. Er ist geeignet, Calreticulin in Proben von Schwein zu detektieren.

Kurzübersicht für Calreticulin Antikörper (AA 18-417) (ABIN7178241)

Target: Calreticulin (CALR)

Reaktivität: Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calreticulin Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-Calreticulin Antikörper

Bindungsspezifität: AA 18-417

Kreuzreaktivität: Schwein

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Pig Calreticulin protein (18-417AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Calreticulin

Target: Calreticulin (CALR)

Andere Bezeichnung: CALR

Hintergrund:

Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.

Aliases: CALRCalreticulin antibody, CRP55 antibody, Calregulin antibody, Endoplasmic reticulum resident protein 60 antibody, ERp60 antibody, HACBP antibody

UniProt: P28491

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response