Perforin 1 Antikörper (AA 21-554)
Kurzübersicht für Perforin 1 Antikörper (AA 21-554) (ABIN7177734)
Target
Alle Perforin 1 (PRF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 21-554
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                                            Kreuzreaktivität
- Human, Maus
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                                            Aufreinigung
- >95%, Protein G purified
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                                            Immunogen
- Recombinant Mouse Perforin-1 protein (21-554AA)
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Buffer
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
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                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C,-80 °C
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                                            Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
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                                            Andere Bezeichnung
- Prf1
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                                            Hintergrund
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                        Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. Aliases: Prf1 antibody, Pfp antibody, Perforin-1 antibody, P1 antibody, Cytolysin antibody, Lymphocyte pore-forming protein antibody 
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                                            UniProt
- P10820
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                                            Pathways
- Apoptose, Caspase Kaskade in der Apoptose
 Target
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