RAD23A Antikörper (AA 2-201) (Biotin)

Produktnummer ABIN7175171

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAD23A in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RAD23A Antikörper (AA 2-201) (Biotin) (ABIN7175171)

Target: RAD23A (RAD23 Homolog A (RAD23A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD23A Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-RAD23A Antikörper (Biotin)

Bindungsspezifität: AA 2-201

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human UV excision repair protein RAD23 homolog A protein (2-201AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Andere Bezeichnung: RAD23A

Hintergrund:

Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to \\\'Lys-48\\\'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to \\\'Lys-63\\\'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.

Aliases: hHR 23A antibody, hHR23A antibody, HR23A antibody, MGC111083 antibody, RAD 23a antibody, RAD23 homolog A (S. cerevisiae) antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23A antibody, RD23A_HUMAN antibody, UV excision repair protein RAD23 antibody, UV excision repair protein RAD23 homolog A antibody

UniProt: P54725

Pathways: DNA Reparatur