RAD23A Antikörper (AA 2-201)

Produktnummer ABIN7175170

Produktdetails anti-RAD23A Antikörper

Target: RAD23A (RAD23 Homolog A (RAD23A))

Bindungsspezifität: AA 2-201

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human UV excision repair protein RAD23 homolog A protein (2-201AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Andere Bezeichnung: RAD23A (RAD23A Produkte)

Synonyme: rad23a antikoerper, wu:fe11h06 antikoerper, zgc:92001 antikoerper, RAD23A antikoerper, HHR23A antikoerper, HR23A antikoerper, 2310040P19Rik antikoerper, AL024030 antikoerper, mHR23A antikoerper, RAD23 homolog A, nucleotide excision repair protein a antikoerper, RAD23 homolog A, nucleotide excision repair protein antikoerper, rad23aa antikoerper, RAD23A antikoerper, Rad23a antikoerper

Hintergrund:

Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to \\\'Lys-48\\\'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to \\\'Lys-63\\\'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.

Aliases: hHR 23A antibody, hHR23A antibody, HR23A antibody, MGC111083 antibody, RAD 23a antibody, RAD23 homolog A (S. cerevisiae) antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23A antibody, RD23A_HUMAN antibody, UV excision repair protein RAD23 antibody, UV excision repair protein RAD23 homolog A antibody

UniProt: P54725

Pathways: DNA Reparatur