ROR2 Antikörper (AA 752-926)

Produktnummer ABIN7174072

Dieses Anti-ROR2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ROR2 in IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für ROR2 Antikörper (AA 752-926) (ABIN7174072)

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ROR2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-ROR2 Antikörper

Bindungsspezifität: AA 752-926

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 protein (752-926AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ROR2

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Andere Bezeichnung: ROR2

Hintergrund:

Background: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).

Aliases: BDB antibody, BDB1 antibody, Brachydactyly type B antibody, EC 2.7.10.1 antibody, MGC163394 antibody, Neurotrophic tyrosine kinase antibody, Neurotrophic tyrosine kinase, receptor related 2 antibody, NTRKR2 antibody, Receptor tyrosine kinase-like orphan receptor 2 antibody, receptor-related 2 antibody, ROR2 antibody, ROR2_HUMAN antibody, Tyrosine protein kinase transmembrane receptor ROR2 antibody, Tyrosine-protein kinase transmembrane receptor Ror2 antibody

UniProt: Q01974

Pathways: RTK Signalweg, WNT Signalweg