TWIST1 Antikörper (AA 1-80) (HRP)

Produktnummer ABIN7173948

Produktdetails anti-TWIST1 Antikörper (HRP)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Bindungsspezifität: AA 1-80

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWIST1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Twist-related protein 1 protein (1-80AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Andere Bezeichnung: TWIST1 (TWIST1 Produkte)

Hintergrund:

Background: Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).

Aliases: ACS3 antibody, B-HLH DNA binding protein antibody, bHLHa38 antibody, BPES2 antibody, BPES3 antibody, Class A basic helix-loop-helix protein 38 antibody, CRS antibody, CRS1 antibody, CSO antibody, H-twist antibody, OTTHUMP00000116043 antibody, SCS antibody, Twist basic helix loop helix transcription factor 1 antibody, Twist family bHLH transcription factor 1 antibody, Twist homolog 1 (Drosophila) antibody, Twist homolog 1 antibody, TWIST homolog of drosophila antibody, Twist related protein 1 antibody, Twist-related protein 1 antibody, TWIST1 antibody, TWST1_HUMAN antibody

UniProt: Q15672

Pathways: p53 Signalweg, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity