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TWIST1 Antikörper (C-Term)

TWIST1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Pferd, Schwein, Hund, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780347
  • Target Alle TWIST1 Antikörper anzeigen
    TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 66
    • 25
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Pferd, Schwein, Hund, Kaninchen, Meerschweinchen
    Wirt
    • 34
    • 29
    • 3
    Kaninchen
    Klonalität
    • 39
    • 27
    Polyklonal
    Konjugat
    • 46
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser TWIST1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 25
    • 13
    • 11
    • 10
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    DKLSKIQTLK LAARYIDFLY QVLQSDELDS KMASCSYVAH ERLSYAFSVW
    Homologie
    Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TWIST1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human TWIST1
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 202 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

  • Target
    TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))
    Andere Bezeichnung
    TWIST1 (TWIST1 Produkte)
    Synonyme
    scs antikoerper, Xtwi antikoerper, acs3 antikoerper, X-twi antikoerper, bpes2 antikoerper, bpes3 antikoerper, twist antikoerper, Xtwist antikoerper, MGC69439 antikoerper, twist1 antikoerper, ACS3 antikoerper, BPES2 antikoerper, BPES3 antikoerper, CRS1 antikoerper, SCS antikoerper, TWIST antikoerper, bHLHa38 antikoerper, AA960487 antikoerper, M-Twist antikoerper, Pde antikoerper, Ska10 antikoerper, Ska antikoerper, Twist antikoerper, pdt antikoerper, cTwist antikoerper, Twist1b antikoerper, twist-1 antikoerper, wu:fd04c01 antikoerper, zgc:101115 antikoerper, twist family bHLH transcription factor 1 antikoerper, twist family bHLH transcription factor 1 S homeolog antikoerper, twist basic helix-loop-helix transcription factor 1 antikoerper, twist homolog 1 (Drosophila) antikoerper, twist family bHLH transcription factor 1a antikoerper, TWIST1 antikoerper, twist1 antikoerper, twist1.S antikoerper, Twist1 antikoerper, twist1a antikoerper
    Hintergrund
    Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation.TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
    Alias Symbols: SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38
    Protein Interaction Partner: UBC, HOXA5, ETS2, TP53, KAT2B, SETD8, HES6, MTA2, BRAP, TCF3, RELA, PPP2CA, HDAC2, CHD3, TWIST2, ELSPBP1, WDR5, HDAC3, RBBP7, CHD4, SOX2, EP300, TWIST1, GLI3, MYOD1,
    Protein Size: 202
    Molekulargewicht
    21 kDa
    Gen-ID
    7291
    NCBI Accession
    NM_000474, NP_000465
    UniProt
    Q15672
    Pathways
    p53 Signalweg, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity
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