TWIST1 Antikörper (Center)

Produktnummer ABIN2854290

Produktdetails anti-TWIST1 Antikörper

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWIST1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Huhn, Rind (Kuh)

Kreuzreaktivität (Details): Chicken (82 %), Bovine (97 %)

Produktmerkmale: Rabbit Polyclonal antibody to TWIST1 (twist homolog 1 (Drosophila))
Twist1 antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Twist1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:5000-1:20000*

Kommentare:

Positive Control: Flag-human TWIST1-transfected HeLa cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-TWIST1 Antikörper (ABIN2854290)

Lee, Chen, Chen, Yang, Huang, Liu: "Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells." in: PLoS ONE, Vol. 12, Issue 7, pp. e0180383, (2017) (PubMed).

Details zu TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Andere Bezeichnung: Twist1 (TWIST1 Produkte)

Synonyme: scs antikoerper, Xtwi antikoerper, acs3 antikoerper, X-twi antikoerper, bpes2 antikoerper, bpes3 antikoerper, twist antikoerper, Xtwist antikoerper, MGC69439 antikoerper, twist1 antikoerper, ACS3 antikoerper, BPES2 antikoerper, BPES3 antikoerper, CRS1 antikoerper, SCS antikoerper, TWIST antikoerper, bHLHa38 antikoerper, AA960487 antikoerper, M-Twist antikoerper, Pde antikoerper, Ska10 antikoerper, Ska antikoerper, Twist antikoerper, pdt antikoerper, cTwist antikoerper, Twist1b antikoerper, twist-1 antikoerper, wu:fd04c01 antikoerper, zgc:101115 antikoerper, twist family bHLH transcription factor 1 antikoerper, twist family bHLH transcription factor 1 S homeolog antikoerper, twist basic helix-loop-helix transcription factor 1 antikoerper, twist homolog 1 (Drosophila) antikoerper, twist family bHLH transcription factor 1a antikoerper, TWIST1 antikoerper, twist1 antikoerper, twist1.S antikoerper, Twist1 antikoerper, twist1a antikoerper

Hintergrund: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Cellular Localization: Nucleus

Molekulargewicht: 21 kDa

Gen-ID: 7291

Pathways: p53 Signalweg, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity