RPS6KA3 Antikörper (pSer369)

Produktnummer ABIN713126

Der Kaninchen Polyklonal Anti-RPS6KA3-Antikörper wurde für WB, ELISA, IF (p), IF (cc), IHC (p) und IHC (fro) validiert. Er ist geeignet, RPS6KA3 in Proben von Human zu detektieren.

Kurzübersicht für RPS6KA3 Antikörper (pSer369) (ABIN713126)

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-RPS6KA3 Antikörper

Bindungsspezifität: pSer369

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human RSK2 around the phosphorylation site of Ser369 [KD(p-S)PG]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Andere Bezeichnung: RSK2

Hintergrund:

Synonyms: RPS6KA3phospho S369, Rsk 2, MAPKAP Kinase 1b, MAP kinase activated protein kinase 1b, MAPK activated protein kinase 1b, 90 kDa ribosomal protein S6 kinase 3, HU2, HU3, Insulin stimulated protein kinase 1, ISPK1, MAPKAPK 1b, MAPKAPK1B, MRX19, p90 RSK3, p90RSK3, pp90RSK2, Ribosomal protein S6 kinase 90 kDa polypeptide 3, Ribosomal protein S6 kinase alpha 3, Ribosomal S6 kinase 2, RPS6KA3, S6 kinase 2, S6K alpha3, KS6A3_HUMAN.

Background: RSK2 or MAPKAP Kinase 1b is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates including ribosomal protein S6 and members of the mitogen activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin Lowry syndrome.

Gen-ID: 6197

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades