TCHP Antikörper (AA 1-498) (Biotin)

Produktnummer ABIN7173374

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TCHP in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TCHP Antikörper (AA 1-498) (Biotin) (ABIN7173374)

Target: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCHP Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-TCHP Antikörper (Biotin)

Bindungsspezifität: AA 1-498

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TCHP

Target: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Andere Bezeichnung: TCHP

Hintergrund:

Background: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).

Aliases: TCHP antibody, Trichoplein keratin filament-binding protein antibody, Protein TCHP antibody, Mitochondrial protein with oncostatic activity antibody, Mitostatin antibody, Tumor suppressor protein antibody

UniProt: Q9BT92