Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) Antikörper

Details zu Produkt Nr. ABIN955129, Anbieter: Anmelden zum Anzeigen
Antigen
  • TpMs
  • A930031F18Rik
  • AV279199
  • RGD1310813
  • zgc:136634
  • trichoplein keratin filament binding
  • trichoplein, keratin filament binding
  • trichoplein, keratin filament binding L homeolog
  • TCHP
  • tchp
  • Tchp
  • tchp.L
Epitop
AA 306-370, Middle Region
10
8
7
7
4
3
1
Reaktivität
Human
49
18
18
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
48
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
31
22
19
16
13
8
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide between 306~370 amino acids from the Center region of human TCHP
Isotyp Ig Fraction
Spezifität This antibody detects TCHP (Center).
Kreuzreaktivität (Details) Species reactivity (tested):Human
Reinigung Protein A column; followed by peptide affinity purification
Antigen
Andere Bezeichnung TCHP (TCHP Antibody Abstract)
Hintergrund TCHP may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. This protein may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.Synonyms: Mitochondrial protein with oncostatic activity, Mitostatin, Trichoplein keratin filament-binding protein
Gen-ID 84260
NCBI Accession NP_001137324
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) antibody (ABIN955129) TCHP Antibody (Center) flow cytometric analysis of CEM cells (bottom histogram) compa...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) antibody (ABIN955129) Formalin-fixed and paraffin-embedded human skin tissue reacted with TCHP Antibody (Ce...
Western Blotting (WB) image for anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) antibody (ABIN955129) Western blot analysis of TCHP Antibody (Center) in CEM cell line lysates (35 µg/lane)...
Allgemeine Veröffentlichungen Vecchione, Fassan, Anesti, Morrione, Goldoni, Baldassarre, Byrne, DArca, Palazzo, Lloyd, Scorrano, Gomella, Iozzo, Baffa: "MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer." in: Oncogene, Vol. 28, Issue 2, pp. 257-69, 2009 (PubMed).

Snow, Callan: "Evidence for a polarized movement of the lateral loops of newt lampbrush chromosomes during oogenesis." in: Journal of cell science, Vol. 5, Issue 1, pp. 1-25, 1970 (PubMed).

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