ROCK2 Antikörper (pTyr256)

Produktnummer ABIN713096

Der Kaninchen Polyklonal Anti-ROCK2-Antikörper wurde für ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und FACS validiert. Er ist geeignet, ROCK2 in Proben von Human, Ratte und Maus zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ROCK2 Antikörper (pTyr256) (ABIN713096)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ROCK2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Produktdetails anti-ROCK2 Antikörper

Bindungsspezifität: pTyr256

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ROCK2 around the phosphorylation site of Tyr256

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ROCK2 Antikörper (ABIN713096)

Achiron, Feldman, Karmona, Avizemer, Barequet, Rosner, Knyazer, Bartov, Burgansky, Vishnevskia-Dai: "Prophylactic exposure of human corneal endothelial cells to Rho-associated kinase inhibitor reduced apoptosis rate after phacoemulsification: Ex vivo study." in: Journal of cataract and refractive surgery, Vol. 44, Issue 10, pp. 1261-1266, (2019) (PubMed).

Details zu ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Andere Bezeichnung: ROCK2

Hintergrund:

Synonyms: ROCK2phospho Y256, p164 ROCK 2, Rho associated coiled coil containing protein kinase 2, Rho associated protein kinase 2, Rho kinase 2, ROCK 2, Rock II, Rock2m, ROK alpha, ROKalpha, ROCK2_HUMAN.

Background: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

Gen-ID: 9475

Pathways: Microtubule Dynamics, WNT Signalweg, Tube Formation