SOCS4 Antikörper (AA 1-270)

Produktnummer ABIN7171004

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SOCS4 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SOCS4 Antikörper (AA 1-270) (ABIN7171004)

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SOCS4 Antikörper

Bindungsspezifität: AA 1-270

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Suppressor of cytokine signaling 4 protein (1-270AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SOCS4

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Andere Bezeichnung: SOCS4

Hintergrund:

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.

Aliases: CIS4 antibody, Cish4 antibody, Cytokine inducible SH2 protein 4 antibody, DKFZp686J1568 antibody, HSPC060 antibody, SH2 domain containing SOCS box protein antibody, SOCS-4 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS4_HUMAN antibody, SOCS6 antibody, SOCS7 antibody, SSI4 antibody, STAI4 antibody, STAT induced STAT inhibitor 4 antibody, STAT4 antibody, STATI4 antibody, Suppressor of cytokine signaling 4 antibody, Suppressor of cytokine signaling 7 antibody

UniProt: Q8WXH5

Pathways: JAK-STAT Signalweg, EGFR Signaling Pathway