SOCS4 Antikörper (AA 1-270)
Kurzübersicht für SOCS4 Antikörper (AA 1-270) (ABIN7171004)
Target
Alle SOCS4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-270
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Suppressor of cytokine signaling 4 protein (1-270AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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Andere Bezeichnung
- SOCS4
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Hintergrund
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Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
Aliases: CIS4 antibody, Cish4 antibody, Cytokine inducible SH2 protein 4 antibody, DKFZp686J1568 antibody, HSPC060 antibody, SH2 domain containing SOCS box protein antibody, SOCS-4 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS4_HUMAN antibody, SOCS6 antibody, SOCS7 antibody, SSI4 antibody, STAI4 antibody, STAT induced STAT inhibitor 4 antibody, STAT4 antibody, STATI4 antibody, Suppressor of cytokine signaling 4 antibody, Suppressor of cytokine signaling 7 antibody
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UniProt
- Q8WXH5
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Pathways
- JAK-STAT Signalweg, EGFR Signaling Pathway
Target
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