SOCS4 Antikörper (AA 227-254)
Kurzübersicht für SOCS4 Antikörper (AA 227-254) (ABIN3029046)
Target
Alle SOCS4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 227-254
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Verwendungszweck
- SOCS4 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot the SOCS4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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Andere Bezeichnung
- SOCS4
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Hintergrund
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
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UniProt
- Q8WXH5
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Pathways
- JAK-STAT Signalweg, EGFR Signaling Pathway
Target
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