SKA3 Antikörper (AA 101-195)

Produktnummer ABIN7170595

Dieses Anti-SKA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SKA3 in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für SKA3 Antikörper (AA 101-195) (ABIN7170595)

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKA3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SKA3 Antikörper

Bindungsspezifität: AA 101-195

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SKA3

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Andere Bezeichnung: SKA3

Hintergrund:

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).

Aliases: C13orf3 antibody, RAMA1 antibody, SKA3 antibody, SKA3_HUMAN antibody, Spindle and kinetochore associated complex subunit 3 antibody, Spindle and kinetochore-associated protein 3 antibody

UniProt: Q8IX90