Sonic Hedgehog Antikörper (AA 51-300)
Kurzübersicht für Sonic Hedgehog Antikörper (AA 51-300) (ABIN7170326)
Target
Alle Sonic Hedgehog (SHH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 51-300
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Sonic hedgehog protein (51-300AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Sonic Hedgehog (SHH)
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Andere Bezeichnung
- SHH
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Hintergrund
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Background: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
Aliases: HHG 1 antibody, HHG-1 antibody, HHG1 antibody, HLP 3 antibody, HLP3 antibody, Holoprosencephaly 3 antibody, HPE 3 antibody, HPE3 antibody, MCOPCB5 antibody, shh antibody, SHH_HUMAN antibody, SMMC I antibody, SMMCI antibody, Sonic Hedgehog (Drosophila) homolog antibody, sonic hedgehog homolog (Drosophila) antibody, Sonic hedgehog homolog antibody, Sonic hedgehog protein antibody, Sonic hedgehog protein C-product antibody, TPT antibody, TPTPS antibody
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UniProt
- Q15465
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Pathways
- Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
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