Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SPPL2B Antikörper (AA 492-592) (FITC)

Dieses Anti-SPPL2B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPPL2B in . Geeignet für Human.
Produktnummer ABIN7169629

Kurzübersicht für SPPL2B Antikörper (AA 492-592) (FITC) (ABIN7169629)

Target

Alle SPPL2B Antikörper anzeigen
SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Reaktivität

  • 11
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 11
Kaninchen

Klonalität

  • 11
Polyklonal

Konjugat

  • 9
  • 1
  • 1
Dieser SPPL2B Antikörper ist konjugiert mit FITC

Applikation

Bitte anfragen
  • Bindungsspezifität

    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 492-592

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Signal peptide peptidase-like 2B protein (492-592AA)

    Isotyp

    IgG
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

    Andere Bezeichnung

    SPPL2B

    Hintergrund

    Background: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing (PubMed:16829952, PubMed:16829951, PubMed:17965014, PubMed:19114711, PubMed:22194595). Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus (PubMed:16829952, PubMed:16829951). May play a role in the regulation of innate and adaptive immunity (PubMed:16829952). Catalyzes the intramembrane cleavage of the simian foamy virus processed leader peptide gp18 of the envelope glycoprotein gp130 dependently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis (PubMed:23132852).

    Aliases: SPPL2B antibody, IMP4 antibody, KIAA1532 antibody, PSL1 antibody, Signal peptide peptidase-like 2B antibody, SPP-like 2B antibody, SPPL2b antibody, EC 3.4.23.- antibody, Intramembrane protease 4 antibody, IMP-4 antibody, Presenilin homologous protein 4 antibody, PSH4 antibody, Presenilin-like protein 1 antibody

    UniProt

    Q8TCT7
Sie sind hier:
Chat with us!