ERN1 Antikörper (AA 493-561) (Biotin)

Produktnummer ABIN7169239

Dieses Anti-ERN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ERN1 in ELISA. Geeignet für Human.

Kurzübersicht für ERN1 Antikörper (AA 493-561) (Biotin) (ABIN7169239)

Target: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERN1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-ERN1 Antikörper (Biotin)

Bindungsspezifität: AA 493-561

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERN1

Target: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Andere Bezeichnung: ERN1

Hintergrund:

Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Aliases: Endoplasmic reticulum (ER) to nucleus signalling 1 antibody, Endoplasmic reticulum to nucleus signaling 1 antibody, Endoplasmic reticulum-to-nucleus signaling 1 antibody, Endoribonuclease antibody, ER to nucleus signaling 1 antibody, ERN 1 antibody, Ern1 antibody, ERN1_HUMAN antibody, hIRE 1p antibody, hIRE1p antibody, Inositol requiring 1 antibody, Inositol requiring 1, S. cerevisiae, homolog of antibody, Inositol requiring enzyme 1, S. cerevisiae, homolog of antibody, Inositol requiring protein 1 antibody, inositol-requiring enzyme 1 antibody, Inositol-requiring protein 1 antibody, IRE 1 antibody, IRE 1a antibody, IRE 1P antibody, Ire1 alpha antibody, Ire1-alpha antibody, IRE1a antibody, Ire1alpha antibody, IRE1P antibody, MGC163277 antibody, MGC163279 antibody, Protein kinase/endoribonuclease antibody, RGD1559716 antibody, Serine/threonine protein kinase/endoribonuclease IRE1 antibody

UniProt: O75460

Pathways: ER-Nucleus Signaling, Unfolded Protein Response