SFRP1 Antikörper (AA 170-240) (FITC)

Produktnummer ABIN7168679

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SFRP1 in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SFRP1 Antikörper (AA 170-240) (FITC) (ABIN7168679)

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP1 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-SFRP1 Antikörper (FITC)

Bindungsspezifität: AA 170-240

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Secreted frizzled-related protein 1 protein (170-240AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1

Hintergrund:

Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Aliases: Frizzled related protein 1 antibody, FRP 1 antibody, FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP-2 antibody, SARP2 antibody, Secreted apoptosis related protein 2 antibody, Secreted apoptosis-related protein 2 antibody, Secreted frizzled related protein 1 antibody, Secreted frizzled related protein antibody, Secreted frizzled-related protein 1 antibody, SFRP 1 antibody, sFRP-1 antibody, SFRP1 antibody, SFRP1_HUMAN antibody

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation