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Rubicon Antikörper (AA 518-733)

KIAA0226 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7168473
  • Target Alle Rubicon (KIAA0226) Antikörper anzeigen
    Rubicon (KIAA0226) (KIAA0226)
    Bindungsspezifität
    • 18
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 518-733
    Reaktivität
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 2
    Kaninchen
    Klonalität
    • 31
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Rubicon Antikörper ist unkonjugiert
    Applikation
    • 30
    • 18
    • 14
    • 13
    • 10
    • 9
    • 5
    • 3
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (518-733AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KIAA0226 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:200-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Rubicon (KIAA0226) (KIAA0226)
    Andere Bezeichnung
    RUBCN (KIAA0226 Produkte)
    Synonyme
    RUBICON antikoerper, 5330403K09 antikoerper, Kiaa0226 antikoerper, Rubicon antikoerper, mKIAA0226 antikoerper, RUN and cysteine rich domain containing beclin 1 interacting protein antikoerper, KIAA0226 antikoerper, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antikoerper, RUBCN antikoerper, KIAA0226 antikoerper, Rubcn antikoerper
    Hintergrund

    Background: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745).

    Aliases: Baron antibody, Beclin 1 associated RUN domain containing protein antibody, Beclin-1 associated RUN domain containing protein antibody, hypothetical protein LOC9711 antibody, Kiaa0226 antibody, OTTHUMP00000208021 antibody, OTTHUMP00000208023 antibody, OTTHUMP00000208024 antibody, RUBIC_HUMAN antibody, Rubicon antibody, RUN domain and cysteine rich domain containing, Beclin 1 interacting protein antibody, Run domain Beclin 1 interacting and cystein rich containing protein antibody, Run domain Beclin-1 interacting and cysteine-rich containing protein antibody, RUN domain protein as Beclin 1 interacting and cysteine rich containing antibody

    UniProt
    Q92622
    Pathways
    Autophagie
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