S100B Antikörper (AA 1-92)

Produktnummer ABIN7166082

Der Kaninchen Polyklonal Anti-S100B-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, S100B in Proben von Human zu detektieren.

Kurzübersicht für S100B Antikörper (AA 1-92) (ABIN7166082)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-S100B Antikörper

Bindungsspezifität: AA 1-92

Verwendungszweck: S100B Antibody

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Protein S100-B protein (1-92AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S100B

Hintergrund:

Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Aliases: NEF antibody, Protein S100 B antibody, Protein S100-B antibody, S 100 calcium binding protein beta chain antibody, S 100 protein beta chain antibody, S-100 protein beta chain antibody, S-100 protein subunit beta antibody, S100 antibody, S100 calcium binding protein beta (neural) antibody, S100 calcium-binding protein B antibody, S100 protein beta chain antibody, S100B antibody, S100B_HUMAN antibody, S100beta antibody

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine