PSMA7 Antikörper (AA 5-232) (Biotin)

Produktnummer ABIN7164965

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PSMA7 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PSMA7 Antikörper (AA 5-232) (Biotin) (ABIN7164965)

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA7 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-PSMA7 Antikörper (Biotin)

Bindungsspezifität: AA 5-232

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Proteasome subunit alpha type-7 protein (5-232AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PSMA7

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Andere Bezeichnung: PSMA7

Hintergrund:

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response

Aliases: C6 antibody, HSPC antibody, MGC3755 antibody, OTTHUMP00000031449 antibody, OTTHUMP00000031450 antibody, OTTHUMP00000031453 antibody, Proteasome (prosome macropain) subunit alpha type 7 antibody, Proteasome alpha 7 subunit antibody, Proteasome subunit alpha 4 antibody, Proteasome subunit alpha type 7 antibody, Proteasome subunit alpha type-7 antibody, Proteasome subunit RC6 1 antibody, Proteasome subunit RC6-1 antibody, Proteasome subunit XAPC7 antibody, PSA7_HUMAN antibody, PSMA 7 antibody, PSMA7 antibody, RC6 1 antibody, XAPC7 antibody

UniProt: O14818

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA