Presenilin 2 Antikörper (AA 7-77) (Biotin)

Produktnummer ABIN7164269

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Presenilin 2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Presenilin 2 Antikörper (AA 7-77) (Biotin) (ABIN7164269)

Target: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Presenilin 2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Presenilin 2 Antikörper (Biotin)

Bindungsspezifität: AA 7-77

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Presenilin-2 protein (7-77AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Presenilin 2

Target: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Andere Bezeichnung: PSEN2

Hintergrund:

Background: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

Aliases: AD3L antibody, AD3LP antibody, AD4 antibody, AD5 antibody, Alzheimer disease 4 antibody, CMD1V antibody, E5-1 antibody, OTTHUMP00000035671 antibody, OTTHUMP00000035672 antibody, OTTHUMP00000228286 antibody, OTTHUMP00000228288 antibody, Presenilin 2 (Alzheimer disease 4) antibody, Presenilin 2 antibody, Presenilin-2 CTF subunit antibody, PS-2 antibody, PS2 antibody, Psen2 antibody, PSN2_HUMAN antibody, PSNL2 antibody, STM-2 antibody, STM2 antibody

UniProt: P49810

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung