Presenilin 2 Antikörper
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- Target Alle Presenilin 2 (PSEN2) Antikörper anzeigen
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Presenilin 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant protein of human PSEN2.
- Isotyp
- IgG
- Top Product
- Discover our top product PSEN2 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
- Andere Bezeichnung
- PSEN2 (PSEN2 Produkte)
- Synonyme
- AD3L antikoerper, AD4 antikoerper, CMD1V antikoerper, PS2 antikoerper, STM2 antikoerper, ALG-3 antikoerper, Ad4h antikoerper, Alg3 antikoerper, PS-2 antikoerper, Psnl2 antikoerper, pre2 antikoerper, zf-PS2 antikoerper, PSNL2 antikoerper, PSEN2 antikoerper, ad4 antikoerper, ps2 antikoerper, ad3l antikoerper, stm2 antikoerper, Ps2 antikoerper, presenilin 2 antikoerper, presenilin 2 S homeolog antikoerper, presenilin 2 (Alzheimer disease 4) antikoerper, trefoil factor 1 antikoerper, PSEN2 antikoerper, Psen2 antikoerper, psen2 antikoerper, psen2.S antikoerper, Tff1 antikoerper
- Hintergrund
- Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.,PSEN2,AD3L,AD4,CMD1V,PS2,STM2,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Notch Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,PSEN2
- Molekulargewicht
- 46 kDa/50 kDa
- Gen-ID
- 5664
- UniProt
- P49810
- Pathways
- Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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