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BMI1 Antikörper (AA 1-247) (FITC)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMI1 in . Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7163792

Kurzübersicht für BMI1 Antikörper (AA 1-247) (FITC) (ABIN7163792)

Target

Alle BMI1 Antikörper anzeigen
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reaktivität

  • 139
  • 55
  • 28
  • 10
  • 8
  • 7
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 78
  • 59
  • 6
Kaninchen

Klonalität

  • 78
  • 65
Polyklonal

Konjugat

  • 88
  • 11
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BMI1 Antikörper ist konjugiert mit FITC

Applikation

Bitte anfragen
  • Bindungsspezifität

    • 38
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-247

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Polycomb complex protein BMI-1 protein (1-247AA)

    Isotyp

    IgG
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    Andere Bezeichnung

    BMI1

    Hintergrund

    Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility (PubMed:15386022, PubMed:16359901, PubMed:26151332, PubMed:16714294, PubMed:21772249, PubMed:25355358, PubMed:27827373). The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A (PubMed:21772249, PubMed:25355358). In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:26151332, PubMed:21772249).

    Aliases: B lymphoma Mo MLV insertion region (mouse) antibody, B lymphoma Mo MLV insertion region 1 homolog antibody, Bmi 1 antibody, BMI1 antibody, BMI1 polycomb ring finger oncogene antibody, BMI1_HUMAN antibody, Flvi 2/bmi 1 antibody, FLVI2/BMI1 antibody, MGC12685 antibody, Murine leukemia viral (bmi 1) oncogene homolog antibody, Oncogene BMI 1 antibody, PCGF 4 antibody, PCGF4 antibody, Polycomb complex protein BMI 1 antibody, Polycomb complex protein BMI-1 antibody, Polycomb group protein Bmi1 antibody, Polycomb group ring finger 4 antibody, Polycomb group RING finger protein 4 antibody, RING finger protein 51 antibody, RNF 51 antibody, RNF51 antibody

    UniProt

    P35226

    Pathways

    Zellzyklus, Autophagie
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