PIK3C3 Antikörper (Catalytic Subunit) (Biotin)

Produktnummer ABIN7163160

Der Kaninchen Polyklonal Anti-PIK3C3-Antikörper wurde für ELISA validiert. Er ist geeignet, PIK3C3 in Proben von Human zu detektieren.

Kurzübersicht für PIK3C3 Antikörper (Catalytic Subunit) (Biotin) (ABIN7163160)

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-PIK3C3 Antikörper (Biotin)

Bindungsspezifität: AA 700-850, Catalytic Subunit

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylinositol 3-kinase catalytic subunit type 3 protein (700-850AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PIK3C3

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Andere Bezeichnung: PIK3C3

Hintergrund:

Background: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).

Aliases: hVps34 antibody, MGC61518 antibody, Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody, Phosphatidylinositol 3 kinase class 3 antibody, Phosphatidylinositol 3 kinase p100 subunit antibody, Phosphatidylinositol 3-kinase catalytic subunit type 3 antibody, Phosphatidylinositol 3-kinase p100 subunit antibody, Phosphoinositide 3 kinase class 3 antibody, Phosphoinositide-3-kinase class 3 antibody, PI3 kinase type 3 antibody, PI3-kinase type 3 antibody, PI3K type 3 antibody, Pik3c3 antibody, PK3C3_HUMAN antibody, PtdIns 3 kinase type 3 antibody, PtdIns-3-kinase type 3 antibody, Vps 34 antibody, Vps34 antibody

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagie