NOTCH3 Antikörper (AA 1301-1496) (HRP)
Kurzübersicht für NOTCH3 Antikörper (AA 1301-1496) (HRP) (ABIN7161305)
Target
Alle NOTCH3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1301-1496
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Neurogenic locus notch homolog protein 3 protein (1301-1496AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NOTCH3 (Notch 3 (NOTCH3))
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Andere Bezeichnung
- NOTCH3
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Hintergrund
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Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
Aliases: CADASIL antibody, CASIL antibody, NOTC3_HUMAN antibody, Notch 3 antibody, Notch 3 intracellular domain antibody, Notch homolog 3 antibody, Notch3 antibody
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UniProt
- Q9UM47
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Pathways
- Notch Signalweg
Target
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