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NOTCH3 Antikörper (AA 751-850)

NOTCH3 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1681077
  • Target Alle NOTCH3 Antikörper anzeigen
    NOTCH3 (Notch 3 (NOTCH3))
    Bindungsspezifität
    • 14
    • 11
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    AA 751-850
    Reaktivität
    • 52
    • 17
    • 11
    • 1
    Human
    Wirt
    • 33
    • 19
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 37
    • 21
    Polyklonal
    Konjugat
    • 31
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NOTCH3 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 24
    • 22
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    SDGMGFHCTC PPGVQGRQCE LLSPCTPNPC EHGGRCESAP GQLPVCSCPQ GWQGPRCQQD VDECAGPAPC GPHGICTNLA GSFSCTCHGG YTGPSCDQDI
    Kreuzreaktivität
    Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 751-850 of human NOTCH3 (NP_000426.2).
    Isotyp
    IgG
    Top Product
    Discover our top product NOTCH3 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Andere Bezeichnung
    NOTCH3 (NOTCH3 Produkte)
    Synonyme
    CADASIL antikoerper, CASIL antikoerper, IMF2 antikoerper, AW229011 antikoerper, N3 antikoerper, hpbk antikoerper, fa14b08 antikoerper, notch5 antikoerper, wu:fa14b08 antikoerper, notch 3 antikoerper, NOTCH3 antikoerper, Notch3 antikoerper, notch3 antikoerper
    Hintergrund
    This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).,NOTCH3,CADASIL,CADASIL1,CASIL,IMF2,LMNS,notch 3,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Notch Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,Hematopoietic Progenitors,Neural Stem Cells,Cardiovascular,Heart,Cardiogenesis,NOTCH3
    Molekulargewicht
    243 kDa
    Gen-ID
    4854
    UniProt
    Q9UM47
    Pathways
    Notch Signalweg
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