MME Antikörper (AA 386-617)

Produktnummer ABIN7161162

Der Kaninchen Polyklonal Anti-MME-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, MME in Proben von Human zu detektieren.

Kurzübersicht für MME Antikörper (AA 386-617) (ABIN7161162)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MME Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-MME Antikörper

Bindungsspezifität: AA 386-617

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Neprilysin protein (386-617AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung: MME

Hintergrund:

Background: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).

Aliases: Atriopeptidase antibody, CALLA antibody, CD10 antibody, CD10 antigen antibody, Common acute lymphocytic leukemia antigen antibody, DKFZp686O16152 antibody, EC 3.4.24.11 antibody, Enkephalinase antibody, EPN antibody, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody, Membrane metallo endopeptidase antibody, Membrane metallo endopeptidase variant 1 antibody, Membrane metallo endopeptidase variant 2 antibody, Membrane metalloendopeptidase antibody, Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody, Membrane metalloendopeptidase variant 1 antibody, Membrane metalloendopeptidase variant 2 antibody, MGC126681 antibody, MGC126707 antibody, MME antibody, NEP antibody, NEP_HUMAN antibody, Neprilysin antibody, neprilysin-390 antibody, neprilysin-411 antibody, Neutral endopeptidase 24.11 antibody, Neutral endopeptidase antibody, Neutral endopeptidase, membrane-associated antibody, SFE antibody, Skin fibroblast elastase antibody

UniProt: P08473

Pathways: RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration