NADPH Oxidase 4 Antikörper (AA 210-424)

Produktnummer ABIN7161010

Dieses Anti-NADPH Oxidase 4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NADPH Oxidase 4 in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für NADPH Oxidase 4 Antikörper (AA 210-424) (ABIN7161010)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NADPH Oxidase 4 Antikörper

Bindungsspezifität: AA 210-424

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human NADPH oxidase 4 protein (210-424AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund:

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.

Aliases: Kidney oxidase 1 antibody, Kidney oxidase-1 antibody, Kidney superoxide producing NADPH oxidase antibody, Kidney superoxide-producing NADPH oxidase antibody, KOX 1 antibody, KOX antibody, Kox-1 antibody, KOX1 antibody, NADPH antibody, NADPH oxidase 4 antibody, Nox4 antibody, NOX4_HUMAN antibody, Renal NAD(P)H oxidase antibody, Renal NAD(P)H-oxidase antibody, RENOX antibody

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration